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The test can be carried out comfortably and quickly at home

If folate deficiency is suspected, it is reasonable to give oral folic acid (0.4 1 mg/day) without doing laboratory investigation for deficiency at least until the hemoglobin and mean corpuscular volume normalizes (or longer if the underlying cause cannot be eliminated)

An IV infusion bypasses the gut entirely, delivering B12 alongside hydration and supportive vitamins like vitamin C and zinc directly into the bloodstream

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A settling-in reaction is typically a day or two, occasionally up to three